Injection of the Sphenopalatine Ganglion With C-Arm And Radiofrequency For Trigeminal Neuralgia


  • Muhammad Dwi Satriyanto Abdurrab University Pekanbaru. Eka Hospital Pekanbaru Riau
  • Ketut Ngurah Gunapriya Brawijaya Hospital Jakarta
  • Ristiawan Muji Laksono Brawijaya University Malang
  • Saiful Anwar Hospital Malang East Java



Trigeminal Neuralgia, Sphenopalatine Ganglion, Radiofrequency


Trigeminal Neuralgia (TN) is the most severe pain in the world, where patients experience a painful condition from the face that significantly impacts the quality of life and socio economic function of affected patients. The pathophysiology of TN is still unclear, it is thought that TN occurs due to compression of the root entry zone of the trigeminal nerve near the origin of the brain stem and this local pressure causes demyelination which leads to abnormal depolarization which results in ectopic impulses. The sphenopalatine ganglion is a parasympathetic ganglion that is connected to the trigeminal, facial, and sympathetic systems and consists of somatosensory, sympathetic, and parasympathetic nerve fibers. This ganglion receives sensory impulses from around the face. TN Management can in a way pharmacological and surgical; however, it is not capable in a way of effectively relieving, since the technology of radiofrequency ablation, TN patients can be done with radiofrequency ablation with satisfactory results, even one daycare.


Mahtani AA, Sethu G. Review on trigeminal neuralgia. J Pharm Sci Res. 2016;8(6):570–4.

Zunde J Van. Evidence?Based Interventional Pain Medicine: According to Clinical Diagnoses. Evidence?Based Interventional Pain Medicine. UK: A John Wiley & Sons, Ltd.; 2011.

Ristiawan M. Laksono WH. Overcoming Pain with Intervention Management: Pain Not Related to the Spine. Jakarta: EGC; 2018.

Vardhan H, SS, NN, K S. Recurrent Trigeminal Neuralgia: A Case Series and a Review of the Literature. Cureus. 2022;14(2):2–7.

Thal SC, Engelhard K, Werner C. New cerebral protection strategies. Curr Opin Anaesthesiol [Internet]. 2005;18(5):490–5. Available at:

Piagkou M, Demesticha T. The Pterygopalatine Ganglion and its Role in Various Pain Syndromes?: From Anatomy to Clinical Practice. 2011;1–14.

Stogicza AR, Mansano AM, Trescot A, Staats PS. Interventional pain?: a step-by-step guide for the FIPP exam [Internet]. Switzerland: Springer; 2020. 205 hal. Tersedia pada:

Hauser RA, Lackner JB, Steilen-matias D, Harris DK. A Systematic Review of Dextrose Prolotherapy for Chronic Musculoskeletal Pain. 2016;139–59.

Hauser RA, Lackner JB, Steilen-matias D, Harris DK. A Systematic Review of Dextrose Prolotherapy for Chronic Musculoskeletal Pain. 2016;139–59.

Priyahita AP, Satiti S, Yudiyanta. Patofisiologi Neuralgia Pascaherpetika. Berk Neurosains. 2020;19:1–6.

Shehata E. Prolotherapy with 12 . 5 % dextrose to treat temporomandibular joint dysfunction ( TMD ). 2019;5:15–9.

Kim M, Oh Y, Kim J. Diplopia after maxillary nerve block through the lateral infrazygomatic approach: A case report and literature review. J Pain Res. 2021;14:481–5.

Tolba R, Weiss AL, Denis DJ. Sphenopalatine Ganglion Block and Radiofrequency Ablation?: Technical Notes and Efficacy. 2019;32–7.

Wei K, Ho D, Przkora R, Kumar S. Sphenopalatine ganglion?: block , radiofrequency ablation and neurostimulation - a systematic review. 2017;

Akbas M, Gunduz E, Sanli S, Yegin A. Sphenopalatine ganglion pulsed radiofrequency treatment in patients suffering from chronic face and head pain. Brazilian J Anesthesiol (English Ed [Internet]. 2016;66(1):50–4. Tersedia pada:

Nagib M, Hood P, Matteo J. Sphenopalatine Ganglion Block?: Treatment of Migraine and Trigeminal Neuralgia Associated With Multiple Sclerosis Case Presentation. 2020;12(6).

Levin D, Acquadro M, Cerasuolo J, Gerges F. Sphenopalatine ganglion block for ipsilateral shoulder pain following open pancreaticoduodenectomy. 2022;1–4.

Cruccu G, Finnerup NB, Jensen TS, Scholz J, Sindou M, Svensson P, et al. Trigeminal neuralgia: New classification and diagnostic grading for practice and research. Neurology. 2016;87(2):220–8.

Aljuboori Z, Nauta HJ. Multiple Recurrences of Trigeminal Neuralgia Caused by Deformation of the Trigeminal Nerve. Cureus. 2019;11(12):1–6.

Akbas M, Salem HH, Emara TH, Dinc B, Karsli B. Radiofrequency thermocoagulation in cases of atypical trigeminal neuralgia: a retrospective study. Egypt J Neurol Psychiatry Neurosurg. 2019;55(1):0–3.

Binfalah M, Alghawi E, Shosha E, Alhilly A, Bakhiet M. Sphenopalatine Ganglion Block for the Treatment of Acute Migraine Headache. 2018;2018.